A patient with severe diarrhea has a blood pH of 7.2, which is lower than the normal range. What is the most likely cause of this acidosis?

A Loss of bicarbonate ions in the stool ✓
B Excessive production of lactic acid
C Inadequate excretion of hydrogen ions by the kidneys
D Respiratory alkalosis due to hyperventilation

Explanation

Severe diarrhea can lead to a significant loss of bicarbonate ions in the stool, resulting in metabolic acidosis.

Source

Harrison's Principles of Internal Medicine
Electrolytes and Acid-Base Balance Pathophysiology Gastrointestinal Disorders Hard MEDICAL Confidence: medium