What is the primary mechanism by which peptide hormones, such as insulin, are degraded in the body?

A Proteasomal degradation
B Lysosomal degradation
C Oxidative deamination
D Endopeptidase cleavage ✓

Explanation

Peptide hormones like insulin are primarily degraded through endopeptidase cleavage, which breaks down the peptide bonds within the hormone.

Source

Lehninger Principles of Biochemistry
Protein Metabolism Biochemistry Hormone Degradation Medium MEDICAL Confidence: high