Which of the following types of protein modifications involves the addition of a ubiquitin-like protein modifier to a protein substrate?

A Phosphorylation
B Ubiquitination
C Acetylation
D SUMOylation ✓

Explanation

SUMOylation is a type of post-translational modification that involves the covalent attachment of a small ubiquitin-like modifier (SUMO) protein to a target protein, which can affect its stability, localization, and activity.

Source

Scientific literature
Protein Metabolism Biochemistry Post-Translational Modifications Medium MEDICAL Confidence: high