Which of the following types of protein degradation is characterized by the attachment of ubiquitin molecules to lysine residues on the target protein?

A Proteasomal degradation ✓
B Lysosomal degradation
C Autophagic degradation
D Calpain-mediated degradation

Explanation

Proteasomal degradation involves the attachment of ubiquitin molecules to lysine residues on the target protein, marking it for degradation by the 26S proteasome.

Source

Cell Biology textbooks
Protein Metabolism Cell Biology Protein Degradation Medium MEDICAL Confidence: high