Which of the following transcription factors plays a crucial role in the regulation of hematopoietic stem cell quiescence and self-renewal?

A GATA1
B PU.1
C HOXB4
D BMI1 ✓

Explanation

BMI1 is a transcription factor that plays a crucial role in the regulation of hematopoietic stem cell quiescence and self-renewal.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high