Which of the following tests is used to detect the presence of alloantibodies against red blood cell antigens in a patient's serum, particularly in cases of hemolytic disease of the fetus and newborn?

A Indirect Coombs test ✓
B Direct Coombs test
C Cold agglutinin test
D Enzyme-linked immunosorbent assay (ELISA)

Explanation

The indirect Coombs test is used to detect the presence of alloantibodies against red blood cell antigens in a patient's serum, which is particularly important in cases of hemolytic disease of the fetus and newborn.

Source

National Institute of Health (NIH) guidelines
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high