Which of the following substances can be used as an alternative to LISS (Low Ionic Strength Solution) in the indirect antiglobulin test?

A Polyethylene glycol (PEG) ✓
B Albumin
C Dextran
D Gelatin

Explanation

Polyethylene glycol (PEG) can be used as an alternative to LISS in the indirect antiglobulin test, as it helps to enhance the reactivity of IgG antibodies and improve the sensitivity of the test.

Source

Technical Manual of the American Association of Blood Banks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high