Which of the following statements is true regarding the relationship between homocysteine levels and coagulation?

A Elevated homocysteine levels are associated with an increased risk of thrombosis due to enhanced platelet activation
B Elevated homocysteine levels are associated with an increased risk of thrombosis due to impaired endothelial function ✓
C Elevated homocysteine levels have no effect on coagulation or thrombosis risk
D Elevated homocysteine levels are associated with a decreased risk of thrombosis due to enhanced fibrinolysis

Explanation

Elevated homocysteine levels are associated with an increased risk of thrombosis due to impaired endothelial function, which can lead to a prothrombotic state.

Source

Research articles and reviews on homocysteine and coagulation
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: medium