Which of the following statements is true about the mechanism of action of dabigatran?

A It inhibits the activity of factor Xa
B It promotes the activation of protein C
C It directly inhibits the activity of thrombin ✓
D It enhances the activity of antithrombin III

Explanation

Dabigatran is a direct oral anticoagulant that works by directly inhibiting the activity of thrombin, thereby preventing the conversion of fibrinogen to fibrin.

Source

Pharmacology and Therapeutics: Principles to Practice
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high