Which of the following statements about anemia of chronic disease is true?

A It is characterized by increased levels of transferrin receptors
B It is associated with decreased production of erythropoietin
C It is caused by impaired iron utilization due to hepcidin upregulation ✓
D It typically presents with a normocytic anemia

Explanation

Anemia of chronic disease, also known as anemia of chronic inflammation, is characterized by impaired iron utilization due to hepcidin upregulation, leading to a hypoproliferative anemia.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high