Which of the following stages of hematopoiesis is characterized by the expression of lineage-specific transcription factors?

A Hematopoietic stem cell self-renewal
B Multipotent progenitor cell formation
C Lineage commitment ✓
D Terminal differentiation

Explanation

During lineage commitment, hematopoietic progenitor cells express lineage-specific transcription factors, which direct their differentiation into specific blood cell lineages.

Source

Orkin et al. (2008) Nature Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium