Which of the following proteins is involved in the adhesion of hematopoietic stem cells to the bone marrow niche, and is also involved in the regulation of hematopoietic stem cell quiescence?

A N-cadherin
B E-cadherin
C VCAM-1 ✓
D CD44

Explanation

VCAM-1 (Vascular Cell Adhesion Molecule-1) is involved in the adhesion of hematopoietic stem cells to the bone marrow niche, and is also involved in the regulation of hematopoietic stem cell quiescence.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: medium