Which of the following nutrients plays a crucial role in the regulation of homocysteine levels in the blood, and its deficiency is associated with an increased risk of cardiovascular disease?

A Vitamin B12
B Folic acid
C Vitamin B6
D All of the above ✓

Explanation

Vitamins B12, B6, and folic acid are all involved in the regulation of homocysteine levels in the blood, and deficiencies in these nutrients have been linked to an increased risk of cardiovascular disease.

Source

National Institutes of Health
Metabolic and Nutritional Disorders Nutrition and Metabolism Homocysteine Metabolism Hard MEDICAL Confidence: high