Which of the following lipoproteins is primarily responsible for transporting cholesterol from peripheral tissues to the liver for excretion?

A VLDL (Very-Low-Density Lipoprotein)
B LDL (Low-Density Lipoprotein)
C HDL (High-Density Lipoprotein) ✓
D IDL (Intermediate-Density Lipoprotein)

Explanation

HDL plays a critical role in reverse cholesterol transport, where it collects excess cholesterol from peripheral tissues and transports it to the liver for excretion, thereby helping to maintain healthy cholesterol levels.

Source

National Lipid Association Recommendations
Metabolic and Nutritional Disorders Lipid Metabolism Lipoproteins and Cholesterol Transport Easy MEDICAL Confidence: high