Which of the following laboratory tests is used to detect the presence of alloantibodies against high-frequency red blood cell antigens?

A Indirect Coombs test ✓
B Direct Coombs test
C Enzyme-linked immunosorbent assay (ELISA)
D Polyethylene glycol (PEG) precipitation test

Explanation

The indirect Coombs test is a sensitive assay used to detect the presence of alloantibodies against high-frequency red blood cell antigens, which can help identify individuals at risk of hemolytic transfusion reactions.

Source

Clinical Laboratory Science textbook
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high