Which of the following is a key step in the biosynthesis of cholesterol?

A Hydrolysis of acetyl-CoA
B Condensation of acetoacetyl-CoA and acetyl-CoA ✓
C Isomerization of lanosterol to cholesterol
D Oxidation of squalene to lanosterol

Explanation

The biosynthesis of cholesterol involves the condensation of acetoacetyl-CoA and acetyl-CoA to form HMG-CoA, which is then converted to mevalonate.

Source

Biochemistry textbooks
Lipid Metabolism Biochemistry Cholesterol Biosynthesis Hard MEDICAL Confidence: high