Which of the following is a key regulator of cholesterol homeostasis in the body?

A Sterol regulatory element-binding protein (SREBP) ✓
B Low-density lipoprotein receptor (LDLR)
C HMG-CoA reductase
D Acyl-CoA:cholesterol acyltransferase (ACAT)

Explanation

SREBP is a transcription factor that regulates the expression of genes involved in cholesterol synthesis and uptake, playing a crucial role in maintaining cholesterol homeostasis.

Source

Scientific literature
Lipid Metabolism Molecular Biology Cholesterol Homeostasis Medium MEDICAL Confidence: high