Which of the following is a key regulator of cholesterol homeostasis in the cell?

A SREBP1

B SREBP2 ✓

C PPARα

D LXRα

Explanation

SREBP2 (Sterol Regulatory Element-Binding Protein 2) is a transcription factor that regulates the expression of genes involved in cholesterol biosynthesis and uptake, playing a critical role in maintaining cholesterol homeostasis in the cell.

Mnemonic

'2' for 'two'-fold regulation of cholesterol

Source

Cell Metabolism journal

Lipid Metabolism Cell Biology Cholesterol Homeostasis Hard NURSING Confidence: high

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Which of the following is a key regulator of cholesterol homeostasis in the cell?

Explanation

Mnemonic

Source

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