Which of the following is a consequence of an increased level of methemoglobin in the blood?

A Increased oxygen delivery to the tissues
B Decreased oxygen binding affinity
C Cyanosis and shortness of breath ✓
D Increased risk of bleeding disorders

Explanation

Methemoglobin is a form of hemoglobin that is unable to bind oxygen. An increased level of methemoglobin in the blood can lead to cyanosis (a bluish discoloration of the skin) and shortness of breath due to reduced oxygen delivery to the tissues.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: high