Which of the following genes is associated with the development of congenital amegakaryocytic thrombocytopenia, a disorder characterized by impaired megakaryopoiesis?

Mutations in the MPL gene, which encodes the thrombopoietin receptor, are associated with congenital amegakaryocytic thrombocytopenia, a rare disorder characterized by impaired megakaryopoiesis and thrombocytopenia.