Which of the following fatty acids is primarily responsible for the development of steatosis in non-alcoholic fatty liver disease (NAFLD)?

A Palmitic acid ✓
B Oleic acid
C Linoleic acid
D Arachidonic acid

Explanation

Palmitic acid is a saturated fatty acid that has been implicated in the development of steatosis in NAFLD. It can accumulate in hepatocytes and contribute to lipid peroxidation, inflammation, and fibrosis.

Source

Journal of Clinical Investigation
Metabolic and Nutritional Disorders Gastroenterology Non-Alcoholic Fatty Liver Disease Hard MEDICAL Confidence: medium