Which of the following erythrocyte indices is increased in spherocytosis?

A Mean Corpuscular Volume (MCV)
B Mean Corpuscular Hemoglobin (MCH)
C Mean Corpuscular Hemoglobin Concentration (MCHC) ✓
D Red Cell Distribution Width (RDW)

Explanation

In spherocytosis, the MCHC is increased due to the decreased surface area-to-volume ratio of the spherocytes, resulting in a higher concentration of hemoglobin per unit volume.

Source

Williams Hematology
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high