Which of the following enzymes is involved in the synthesis of heme, a critical component of hemoglobin?

A Aminolevulinic acid synthase (ALAS) ✓
B Ferrochelatase
C Uroporphyrinogen decarboxylase
D Porphobilinogen deaminase

Explanation

Aminolevulinic acid synthase (ALAS) is the first enzyme in the heme biosynthetic pathway and is responsible for converting glycine and succinyl-CoA into aminolevulinic acid.

Source

Biochemistry textbook
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high