Which of the following coagulation disorders is characterized by an autoimmune response against factor VIII, leading to its destruction and resulting in bleeding complications?

A Acquired hemophilia A ✓
B Congenital hemophilia A
C Von Willebrand disease
D Disseminated intravascular coagulation

Explanation

Acquired hemophilia A is a rare coagulation disorder characterized by an autoimmune response against factor VIII, leading to its destruction and resulting in bleeding complications.

Source

UpToDate Clinical Decision Support
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high