Which of the following coagulation disorders is associated with an increased risk of thrombosis due to elevated levels of homocysteine, an amino acid that can damage the endothelium and promote clot formation?

A Homocystinuria ✓
B Factor V Leiden thrombophilia
C Protein C deficiency
D Antithrombin deficiency

Explanation

Homocystinuria is a genetic disorder characterized by elevated levels of homocysteine in the blood, which can lead to endothelial damage, enhance coagulation, and increase the risk of thrombosis.

Source

Medical literature on coagulation disorders and thrombosis
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high