Which of the following cellular mechanisms is involved in the regulation of hematopoietic stem cell self-renewal and differentiation in the bone marrow niche?

A Epigenetic modification ✓
B Autophagy
C Apoptosis
D Telomerase activation

Explanation

Epigenetic modifications play a crucial role in regulating the balance between self-renewal and differentiation of hematopoietic stem cells.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium