Which of the following cell surface receptors plays a crucial role in the homing of hematopoietic stem cells to the bone marrow?

A CXCR4 ✓
B CD34
C CD133
D CD38

Explanation

CXCR4 is a chemokine receptor that interacts with its ligand, CXCL12, to mediate the homing of hematopoietic stem cells to the bone marrow.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high