Which of the following cell surface molecules plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche?

A CD34

B CXCR4 ✓

C CD133

D CD117

Explanation

CXCR4 is a chemokine receptor that plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche, where it interacts with its ligand, CXCL12.

Source

Blood journal

Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: medium

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Which of the following cell surface molecules plays a crucial role in the homing of hematopoietic stem cells to the bone marrow niche?

Explanation

Source

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