Which of the following blood grouping systems is characterized by the presence of a high-frequency antigen that is expressed on the red blood cells of most individuals, but is absent in a small percentage of the population?

A Kell blood group system
B Duffy blood group system
C MNS blood group system
D Vel blood group system ✓

Explanation

The Vel blood group system is characterized by the presence of a high-frequency antigen that is expressed on the red blood cells of most individuals, but is absent in a small percentage of the population.

Source

Transfusion Medicine by Rossi
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: medium