Which of the following blood group antigens is known to be labile and can be destroyed by exposure to heat, enzymes, or chemicals?

A ABO antigens
B Rh antigens
C Kell antigens
D T antigen ✓

Explanation

The T antigen is a labile antigen that can be destroyed by exposure to heat, enzymes, or chemicals, which can lead to false-negative results in blood typing.

Mnemonic

T = Thermolabile

Source

Technical Manual of the American Association of Blood Banks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: medium