Which of the following blood group antigens is associated with an increased risk of transfusion-related acute lung injury (TRALI)?

A Kell antigen
B Duffy antigen
C Human neutrophil antigen (HNA) ✓
D Leukocyte antigen

Explanation

The Human Neutrophil Antigen (HNA) is associated with an increased risk of transfusion-related acute lung injury (TRALI).

Source

National Institutes of Health
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high