Which of the following blood group antigens is associated with a reduced risk of malaria?

A RhD antigen
B Kell antigen
C Duffy antigen ✓
D ABO antigen

Explanation

The Duffy antigen has been associated with a reduced risk of malaria, as the Plasmodium vivax parasite uses the Duffy blood group antigen as a receptor to enter red blood cells.

Source

National Institute of Allergy and Infectious Diseases (NIAID) research
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high