Which of the following blood components is responsible for the regulation of apoptosis in neutrophils?

A Tumor necrosis factor-alpha (TNF-α)
B Interleukin-1 beta (IL-1β)
C Granulocyte-colony stimulating factor (G-CSF) ✓
D Bcl-2-associated X protein (BAX)

Explanation

G-CSF is a cytokine that regulates the survival and apoptosis of neutrophils. It acts by binding to its receptor on the surface of neutrophils, thereby activating signaling pathways that promote cell survival and inhibit apoptosis.

Source

Alberts et al. Molecular Biology of the Cell
Hematology Hematology: Blood Components Hematology: Blood Components Medium MEDICAL Confidence: medium