Which of the following anemias is characterized by a mutation in the HBB gene?

A Sickle cell anemia ✓
B Thalassemia major
C Hereditary spherocytosis
D Glucose-6-phosphate dehydrogenase deficiency

Explanation

Sickle cell anemia is caused by a mutation in the HBB gene, which codes for the beta-globin subunit of hemoglobin.

Source

National Institutes of Health
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high