Which of the following anemias is characterized by a mutation in the TMPRSS6 gene?

A Iron-refractory iron deficiency anemia ✓
B Sideroblastic anemia
C Megaloblastic anemia
D Pernicious anemia

Explanation

Iron-refractory iron deficiency anemia is a rare genetic disorder caused by a mutation in the TMPRSS6 gene, leading to impaired iron regulation and anemia.

Source

National Institutes of Health
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high