Which of the following anemias is associated with an increased risk of developing gastric cancer?

A Iron deficiency anemia
B Vitamin B12 deficiency anemia
C Pernicious anemia ✓
D Sickle cell anemia

Explanation

Pernicious anemia, caused by a lack of intrinsic factor leading to vitamin B12 deficiency, is associated with an increased risk of developing gastric cancer, likely due to chronic atrophic gastritis.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high