Which enzyme's dysfunction is associated with the development of Gaucher's disease, a lysosomal storage disorder?

A Glucocerebrosidase ✓
B Sphingomyelinase
C Hexosaminidase A
D Alpha-galactosidase A

Explanation

Glucocerebrosidase is the enzyme responsible for breaking down glucocerebroside. Its dysfunction leads to Gaucher's disease, a lysosomal storage disorder.

Source

Scriver's The Metabolic and Molecular Bases of Inherited Disease
Enzymes in Disease Biochemistry Lysosomal Storage Disorders Hard MEDICAL Confidence: high