Which enzyme is involved in the pathogenesis of pancreatic cancer by promoting cell proliferation and survival?

A Phospholipase A2

B Protease-activated receptor 2

C Matrix metalloproteinase-7 ✓

D Aurora kinase A

Explanation

Matrix metalloproteinase-7 (MMP-7) is overexpressed in pancreatic cancer and promotes cell proliferation, survival, and metastasis by degrading the extracellular matrix and activating signaling pathways.

Source

Journal of Clinical Oncology

Enzymes in Disease Cancer Biology Pancreatic Cancer Medium MEDICAL Confidence: medium

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Which enzyme is involved in the pathogenesis of pancreatic cancer by promoting cell proliferation and survival?

Explanation

Source

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