Which enzyme is involved in the degradation of homocysteine, and what disease is associated with elevated levels of this amino acid?

A Cystathionine beta-synthase ✓
B Methionine synthase
C Homocysteine methyltransferase
D Betaine-homocysteine methyltransferase

Explanation

Cystathionine beta-synthase is an enzyme involved in the transsulfuration pathway, which degrades homocysteine. Elevated levels of homocysteine are associated with homocystinuria, a genetic disorder.

Source

NCERT Class 12 Biochemistry
Enzymes in Disease Biochemistry Amino Acid Metabolism Hard MEDICAL Confidence: high