Which enzyme is implicated in the pathogenesis of gout, a condition characterized by elevated uric acid levels?

A Xanthine oxidase ✓

B Uricase

C Hypoxanthine-guanine phosphoribosyltransferase

D Adenosine deaminase

Explanation

Xanthine oxidase is involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid, and its inhibition is a therapeutic strategy for managing gout.

Source

Clinical Biochemistry textbook

Enzymes in Disease Biochemistry Purine Metabolism Disorders Hard MEDICAL Confidence: high

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Which enzyme is implicated in the pathogenesis of gout, a condition characterized by elevated uric acid levels?

Explanation

Source

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