Which enzyme is implicated in the development of gout due to its role in purine metabolism?

A Xanthine oxidase ✓
B Alkaline phosphatase
C Lactate dehydrogenase
D Creatine kinase

Explanation

Xanthine oxidase is involved in the conversion of hypoxanthine to xanthine and then to uric acid. Inhibition of this enzyme is a common treatment approach for gout.

Source

Medical Biochemistry textbook
Enzymes in Disease Biochemistry Purine Metabolism Disorders Easy MEDICAL Confidence: high