What is the term for the anemia characterized by a deficiency in the enzyme dihydrofolate reductase, leading to impaired DNA synthesis in red blood cell precursors?

A Megaloblastic anemia ✓
B Sideroblastic anemia
C Normocytic anemia
D Microcytic anemia

Explanation

Dihydrofolate reductase is essential for the synthesis of tetrahydrofolate, which is necessary for DNA synthesis. A deficiency in this enzyme leads to megaloblastic anemia.

Source

Wintrobe's Clinical Hematology
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high