What is the significance of the Haldane effect in relation to oxygen transport by hemoglobin?

A It describes the increase in oxygen binding affinity in response to an increase in pH
B It describes the decrease in oxygen binding affinity in response to an increase in carbon dioxide
C It describes the increase in carbon dioxide transport in response to a decrease in oxygen binding ✓
D It describes the buffering capacity of hemoglobin against changes in blood pH

Explanation

The Haldane effect describes the increase in carbon dioxide transport by hemoglobin in response to a decrease in oxygen binding, which is crucial for facilitating the transport of carbon dioxide from peripheral tissues to the lungs.

Source

Berne and Levy Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: high