What is the significance of the differences in globin chain composition between fetal and adult hemoglobin in terms of oxygen transport?

A Increased oxygen affinity in adult hemoglobin
B Decreased oxygen affinity in fetal hemoglobin
C Enhanced oxygen release to tissues in fetal hemoglobin ✓
D Reduced oxygen binding capacity in adult hemoglobin

Explanation

Fetal hemoglobin has a higher affinity for oxygen due to its different globin chain composition, which allows for more efficient oxygen transfer from the mother's bloodstream to the fetus.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high