What is the significance of Chido and Rodgers blood group antigens?

A They are associated with an increased risk of hemolytic disease of the newborn
B They are related to the expression of glycosphingolipids on red blood cells
C They are involved in the regulation of complement activation ✓
D They are associated with an increased risk of transfusion-related acute lung injury

Explanation

Chido and Rodgers blood group antigens are involved in the regulation of complement activation. They are located on the C4d and C4b components of complement, respectively.

Source

Transfusion Medicine by Simon et al.
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: medium