What is the role of the stromal cell-derived factor 1 (SDF-1) in hematopoiesis?

A It promotes the proliferation of hematopoietic stem cells
B It inhibits the differentiation of hematopoietic progenitor cells
C It regulates the migration and homing of hematopoietic stem cells to the bone marrow ✓
D It suppresses the apoptosis of mature blood cells

Explanation

SDF-1 plays a crucial role in the migration and homing of hematopoietic stem cells to the bone marrow, where they can undergo proliferation and differentiation.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high