What is the role of the Notch signaling pathway in hematopoiesis?

A Regulation of apoptosis
B Maintenance of hematopoietic stem cell self-renewal ✓
C Differentiation of myeloid cells
D Activation of immune cells

Explanation

The Notch signaling pathway plays a crucial role in maintaining the self-renewal of hematopoietic stem cells, allowing them to proliferate and differentiate into various blood cell lineages.

Source

Alberts et al. (2002) Molecular Biology of the Cell
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high