What is the role of Protein C in the coagulation cascade?

A It activates Factor X
B It inhibits the activation of Factor V and Factor VIII ✓
C It enhances the activity of thrombin
D It inhibits the formation of fibrin

Explanation

Protein C is a vitamin K-dependent serine protease that plays a crucial role in the regulation of coagulation. It inhibits the activation of Factor V and Factor VIII, thereby preventing excessive coagulation.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high