What is the role of Notch signaling in the regulation of hematopoietic cell fate decisions?

A It promotes the differentiation of hematopoietic stem cells into myeloid cells
B It inhibits the self-renewal of hematopoietic stem cells
C It regulates the balance between myeloid and lymphoid cell development ✓
D It has no role in hematopoiesis

Explanation

Notch signaling plays a crucial role in regulating the balance between myeloid and lymphoid cell development, influencing the fate decisions of hematopoietic cells.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high