What is the role of hypoxia-inducible factor 1 alpha (HIF-1α) in hematopoiesis?

A Regulation of erythropoietin production ✓
B Maintenance of hematopoietic stem cell quiescence
C Enhancement of megakaryopoiesis
D Inhibition of granulopoiesis

Explanation

HIF-1α plays a crucial role in regulating erythropoietin production in response to hypoxia, which is essential for hematopoiesis.

Source

Scientific literature
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high