What is the role of hepcidin in the regulation of iron metabolism in the body?

A It stimulates the absorption of iron from the gut
B It inhibits the release of iron from macrophages ✓
C It regulates the expression of transferrin receptors
D It increases the excretion of iron in the urine

Explanation

Hepcidin is a hormone that plays a central role in the regulation of iron metabolism. It inhibits the release of iron from macrophages and enterocytes, thereby reducing the amount of iron available for erythropoiesis.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high